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Synthesis of MOF materials based on bioactive liquids L'utilisation des ligands avec une activit biologique prsente un intrt pour : - la libration de compos actif par dgradation du matriau MOF l'encapsulation d'autres molcules actives pour des thrapies combinesThe use of ligands with a biological activity is of interest for: the release of active compound by degradation of the MOF material encapsulation of other active molecules for combined therapies Des tests de l'activit antimicrobienne, ainsi que la dgradation dans des milieux physiologiques et l'activit sur des cellules seront raliss sur des carboxylates de fer poreux a structure flexible de type MIL-88 utilisant les acides 4, 4 'azobenzene dicarboxylique et 3,3 ' -dichlore 4,4 ' -azobenzene dicarboxylique, entre autres.Tests of antimicrobial activity, as well as degradation in physiological media and activity on cells will be performed on porous iron carboxylates with flexible structure of type MIL-88 using 4,4'-azobenzene dicarboxylic acids and 3,3'-4,4'-dichlorobenzene dicarboxylic acid, among others
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Le solide est ensuite rcupr par filtration.To obtain the MIL-88A material, 270 mg of FeCl 3 .6H 2 O (1 mmol, Alfa Aesar, 98%), 112 mg of fumaric acid (1 mmol, Acros, 99%) are mixed in 5 ml of dimethylformamide
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